PQQ is a very potent antioxidant. Some of its hallmarks are the ability to lower blood glucose levels as well as to improve oxygen metabolism. It also beneficially interacts with neurotransmitters by modulating the NMDA receptor site. The NMDA site is the mechanism that overstimulates neurons and is implicated in seizures as well as many neurodegenerative diseases.
Bottle Content: 30 Capsules (20 mg)
Active Ingredient: Pyrroloquinoline Quinone Disodium
Other Ingredients: Rice Flour and Vegi-Cap – Cellulose
Quantity Needed for One-Month Supply: Varies on dosage
Dosage: Dosage is controversial as it is very new. Manufacturer recommends 1 or 2 daily with a do not exceed warning on the bottle. Clinically we have seen patients respond better to higher doses up to 6 a day. We have yet to see any side effects.
Time of Day: Generally anytime. Patients who feel a tremendous amount of energy from PQQ like it better in the morning.
Cautions: None known other than it has only been available for a short time and the real dosage range is not fully understood.
What it Does/How it Works:
PQQ signals the cells to create more mitochondria. The mitochondria are the energy powerhouses of the cells. Practically all degenerative diseases are linked to defective mitochondria, including Type 2 Diabetes, heart failure, Alzheimer’s, and cancer. The mitochondria are the only cellular component other than the nucleus that has its own DNA, which gives it the ability to replicate and increase its numbers inside cells. Generally the only known ways to increase mitochondria are severe calorie restriction or intense cardiovascular training.
One popular biological theory today based on animal research is that the mitochondria, both number and quality determine longevity. In one study researchers looked at the muscle tissue of a 90 year old man and found 95% of the mitochondria were damaged.
PQQ is found throughout the plant kingdom as well as in human milk. People are not capable of synthesizing it, leading some to call it a new vitamin.